Precision Infection Control & Wound Closure

Redefining the standard of wound care, worldwide.

IVT Medical is a pioneering R&D company advancing medical device technology in wound healing and closure, developing affordable, safe and effective state-of-the-art solutions for surgeons and care teams across the globe.

Explore Our Technologies → Scientific Publications

TopClosure® Tension Relief System applied to complex wounds

Vcare α®Regulated NPWT

MeCare α®Portable NPWT

Core proprietary technologies

30+

Peer-reviewed publications

15+

Years of published wound care research

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Civil, military & mass-casualty settings

✓ FDA Cleared Devices ✓ ISO 13485:2016 Certified ✓ Israel MoH (AMAR) Registered

Technological Innovations

Three technologies. One integrated approach.

TopClosure® and regulated negative pressure therapy work together as an integrated approach to early wound closure, built on decades of clinical practice, peer-reviewed research and FDA-cleared devices.

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TopClosure® TRS

The Tension Relief System leverages stress relaxation and mechanical creep to harness the skin's viscoelastic properties, ensuring optimal tension management and enhanced closure of high-tension, difficult-to-heal wounds.

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RNPT

Regulated Negative Pressure Therapy delivers pre-set, controlled negative pressure for removal of exudates and infectious materials, with the FDA-cleared Vcare α® and MeCare α® devices and a patented bleeding control system.

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Research Programs

An active, peer-reviewed research program in advanced wound therapy methods, including ROI-NPT and CITA. These investigational methods are published in leading journals and presented to the scientific community. Explore the research →

Device Innovations

Our product portfolio

From the operating room to the battlefield to community care, devices designed around real clinical needs.

TopClosure®

Dynamic acute & chronic wound closure. Wide stress distribution away from wound edges enables closure of extremely hard-to-close wounds, often eliminating the need for skin grafts or flaps.

Vcare α®

Pre-set regulated negative pressure for open wounds. The only NPWT device in the world with a registered patent for bleeding control, complying with IEC-60601-1-8 standards.

MeCare α®

A portable regulated negative pressure device, FDA 510(k) cleared, extending professional wound therapy to community, rural and low-resource care settings.

Published Research

Science first: from the lab to leading journals

Led by our founder and CEO, Prof. Moris Topaz, MD, PhD, IVT Medical has built its technologies on more than 15 years of basic science and clinical research. The company's investigational methods, including regulated oxygen-enriched negative pressure treatment (ROI-NPT) and targeted in-situ antibiotic administration (CITA), are the subject of studies published in peer-reviewed journals, including JACC.

35+ peer-reviewed publications across wound closure and wound therapy
A NICE medtech innovation briefing in the UK (TopClosure®, MIB97)
Research presented at international scientific meetings

ROI-NPT and CITA are investigational methods. They are not FDA-cleared indications of any IVT Medical device, and their safety and effectiveness for those uses have not been established.

Research & Publications →

Rescue & Military

Proven in trauma, mass-casualty and combat scenarios

TopClosure® TRS has played a crucial role in several wars and military operations, enabling rapid, reversible primary closure of complex wounds in battalion first-aid stations and field hospitals.

Military Applications →

"Big results require big ambitions"

Heraclitus

Ready to learn more?

Download our catalog, browse peer-reviewed research featuring our technologies, or get in touch with our team.

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